Most sanctions are decided in Washington, Brussels and New York. Many of the people who live with their consequences live in Latin America, Africa, Asia and the Middle East. How large the costs are is disputed in research. What is certain is where they arise: in the money families send, in medicines, in wages and food.
Who is under sanctions
In 2024 the economist Francisco Rodríguez counted how many countries are affected by sanctions: 54, around 27 percent of all countries, together accounting for 29 percent of the world economy. In the 1960s it was about 4 percent of countries. The number of cases has also risen: the Global Sanctions Data Base counts 615 active sanctions cases for 2023, after 181 in 2010; 46.5 percent of them were imposed by the US. Behind each case are countries whose hospitals, schools and workshops have to buy, pay and plan differently. Of 31 quantitative studies he reviews, 30 found negative effects on income, poverty, inequality, mortality or human rights. How the number of sanctions has developed since 1950 and who imposes them is shown in the lead article “Who blocks whom”.
The dispute: how many deaths?
In August 2025 The Lancet Global Health published a study by Francisco Rodríguez, Silvio Rendón and Mark Weisbrot. It analyses age-specific mortality in 152 countries from 1971 to 2021 and uses several methods to separate cause from chance. Its result: sanctions of individual states are associated with around 564,258 additional deaths a year, with a range of 367,838 to 760,677, most strongly among children under five. For UN sanctions the authors found no statistical evidence.
The figure should be taken seriously and read with care. It is based on observational data; countries that are sanctioned are often already in crisis or war. The study was funded by the Center for Economic and Policy Research, of which Weisbrot is co-director and which has criticised sanctions for years. And it contradicts another peer-reviewed study: in 2021 Gutmann, Neuenkirch and Neumeier found that UN sanctions lower life expectancy much more than US sanctions, and women more than men. Most studies find that sanctions harm health; how strongly, and which sanctions most, is not settled. A review in BMJ Open from October 2026 found harm in 42 of 43 studies on US sanctions, but called the quality of the studies variable.
The path of money
For many families in the South, money from relatives abroad is the most important income. In 2024 low- and middle-income countries received 685 billion US dollars according to the World Bank estimate, most of it South Asia and Latin America. Where sanctions apply, this path becomes narrower and more expensive: banks withdraw, transfer operators lose their accounts. Why is described in the article “Banks worldwide”.
Billion US dollars by region, World Bank estimate. Total 685 billion US dollars.
| Region | Billion US dollars |
|---|---|
| South Asia | 207 |
| Latin America and Caribbean | 163 |
| East Asia and Pacific | 136 |
| Europe and Central Asia | 64 |
| Middle East and North Africa | 58 |
| Sub-Saharan Africa | 56 |
Source: Ratha, Plaza, Kim, World Bank blog “People Move”, 18 Dec 2024, table 1 (2024 estimate). File daten/weltbank_rueckueberweisungen_2024.csv.
Cases from four world regions
Afghanistan shows how quickly wages stop when money stops. After the Taliban took power in August 2021, payments by development agencies and financial institutions ended; the Red Cross took over the salaries of nearly 10,500 staff in 33 hospitals. Of the central bank’s frozen reserves, the US approved up to 3.5 billion US dollars in September 2022 for a fund in Geneva meant to make targeted payments, for example for electricity imports.
Niger shows that sanctions are not a tool of the North only. After the coup in July 2023 the West African economic community ECOWAS imposed sanctions and closed borders. The UN refugee agency warned that the sanctions had no humanitarian exemption. In December 2023 Oxfam counted more than 4.3 million people in urgent need and 185,000 children who could no longer reach treatment for malnutrition. In February 2024 the community lifted the sanctions.
Syria is the case that now shows what comes after sanctions. The US revoked its sanctions programme on 30 June 2025 and repealed the Caesar Act in December 2025. President Ahmad al-Sharaa spoke of “the first day that Syria is without sanctions”. Whether and how quickly supply and wages recover cannot yet be shown.
Medicine and food: permitted, but hard to get
Almost everywhere food and medicines are exempt, and still they are missing. In 2019 Human Rights Watch documented for Iran that a European manufacturer stopped selling special wound dressings for about 800 people with the skin disease epidermolysis bullosa, and that a children’s cancer centre lacked three chemotherapy drugs on the WHO list in May 2019. In Venezuela Mark Weisbrot and Jeffrey Sachs attributed tens of thousands of deaths to US sanctions from 2017; Ricardo Hausmann and Frank Muci countered that oil output and imports of food and medicine had collapsed before the sanctions, imports by more than 80 percent. The dispute shows how hard it is to separate sanctions from mismanagement. Why what is permitted still gets stuck is described in the lead article “Permitted and still blocked”.
| Region and case | Measure | Documented consequence | What stands against or alongside |
|---|---|---|---|
| Afghanistan | Donor and financial institution funding halted, reserves frozen (2021) | ICRC paid salaries of nearly 10,500 staff in 33 hospitals | Part of the reserves in a fund for targeted payments since 2022; UN exemption for aid since December 2021 |
| Niger | Sanctions of the West African community after the coup (2023) | UNHCR: no humanitarian exemption; Oxfam: 185,000 children without access to malnutrition treatment | Response to a coup; sanctions lifted on 24 Feb 2024 |
| Syria | Comprehensive US and EU sanctions since 2011 | After the 2023 earthquake a dedicated US general licence for 180 days | US programme revoked on 30 Jun 2025, Caesar Act repealed in December 2025 |
| Iran | US sanctions, tightened in 2018 | HRW: special dressings for about 800 patients no longer supplied, chemotherapy drugs missing (2019) | US cites nuclear and missile programmes; food and medicine formally exempt |
| Venezuela | US financial and oil sanctions from 2017 and 2019 | Disputed: CEPR attributed tens of thousands of deaths | Hausmann and Muci: oil output and imports collapsed before the sanctions |
| Cuba | US embargo, tightened in 2026 | Western Union stopped (2025), reportedly about 200 banks withdrew | Payment route via firms under military control; 1,351 political prisoners (September 2026) |
Sources: see list of sources; for Iran and Venezuela the in-depth chapters on this website.
Cuba: the same calculation, two responsible parties
What the table shows for Latin America applies to Cuba: the US embargo hinders payments, imports and credit; some 200 foreign banks have reportedly ended their relations, according to information given to the UN Special Rapporteur. At the same time the Cuban leadership has routed remittances through firms that press reports describe as military-controlled, and it persecutes critics: 1,351 political prisoners in September 2026 according to Prisoners Defenders. According to the statistics office, the population fell to 9.4 million by the end of 2025. Details are in the lead article “Cuba 2026 as a case” and the topic sheet “Migration as a consequence”.
Two perspectives
What those who impose sanctions say
Sanctions respond to war, coups, nuclear programmes or grave human rights violations; the alternative is often not trade but military force or looking away.
Almost all programmes exempt food and medicine. Economists such as Hausmann and Muci argue that in Venezuela oil output and imports collapsed before the sanctions.
What those affected and critics say
Exemptions on paper help little when banks and suppliers withdraw; that hits people, not governments.
In 2025 the UN Special Rapporteur Alena Douhan wrote that de-risking and over-compliance had considerably aggravated the humanitarian situation in Cuba. In 2026 the UN General Assembly called for the 34th time for an end to the embargo; 130 states voted in favour, 17 against.
This piece is information, not legal, investment or health advice. It makes no diagnoses. It reflects the view of the editorial team, relies on the sources listed and names opposing positions. “Helfen statt Blockieren” is non-partisan.
Sources
- Rodríguez, The human consequences of economic sanctions, Journal of Economic Studies 51(4), 2024, 942 to 963, https://doi.org/10.1108/JES-06-2023-0299
- Yalcin, Felbermayr, Kariem, Kirilakha, Kwon, Syropoulos, Yotov, The Global Sanctions Data Base, Release 4, CGPA Working Paper 2025-02, 22 Jan 2025 (not peer-reviewed), https://www.lebow.drexel.edu/sites/default/files/2025-01/wp2025002-global-sanctions-db-v2.pdf
- Rodríguez, Rendón, Weisbrot, Effects of international sanctions on age-specific mortality: a cross-national panel data analysis, The Lancet Global Health 13(8), 2025, e1358 to e1366; funding: Center for Economic and Policy Research (abstract via Europe PMC, PMID 40712610), https://doi.org/10.1016/S2214-109X(25)00189-5
- Gutmann, Neuenkirch, Neumeier, Sanctioned to Death? The Impact of Economic Sanctions on Life Expectancy and its Gender Gap, Journal of Development Studies 57(1), 2021, 139 to 162, https://doi.org/10.1080/00220388.2020.1746277
- Korenstein et al., Health impacts of US international economic sanctions: a scoping review, BMJ Open 16(10), 2026, e123343, https://doi.org/10.1136/bmjopen-2026-123343
- Ratha, Plaza, Kim, World Bank Blogs, Remittance flows to low- and middle-income countries 2024, 18 Dec 2024, https://blogs.worldbank.org/en/peoplemove/in-2024--remittance-flows-to-low--and-middle-income-countries-ar
- US Treasury, JY0947, Afghan Fund, 14 Sep 2022 (copy at FRASER, Federal Reserve Bank of St. Louis), https://fraser.stlouisfed.org/files/docs/publications/treaspr/2022/2022-09-14_jy0947.pdf
- ICRC, Afghanistan: Health care system on life support, 30 Aug 2022, https://www.icrc.org/en/document/afghanistan-health-care-system-life-support
- UN News, UNHCR on Niger: sanctions without humanitarian exemption, August 2023, https://news.un.org/en/story/2023/08/1140167
- Oxfam, ECOWAS’ failure to adopt exemptions to Niger sanctions puts lives of millions of Nigeriens at risk, 12 Dec 2023, https://africa.oxfam.org/latest/press-release/ecowas-failure-adopt-exemptions-niger-sanctions-puts-lives-millions-nigeriens
- allAfrica, Ecowas Lifts Sanctions On Guinea, Mali, Niger, Burkina Faso, 24 Feb 2024, https://allafrica.com/stories/202402240256.html
- Willkie Farr & Gallagher, A New Era: United States Lifts Comprehensive Sanctions on Syria, 2025 (order of 30 Jun 2025), https://complianceconcourse.willkie.com/articles/a-new-era-united-states-lifts-comprehensive-sanctions-on-syria/
- The National, Syria welcomes repeal of sweeping US sanctions (Caesar Act, NDAA 2026), 20 Dec 2025, https://www.thenationalnews.com/news/mena/2025/12/20/syria-welcomes-repeal-of-sweeping-us-sanctions
- US Treasury, JY1261, Syria General License 23, 9 Feb 2023, https://home.treasury.gov/news/press-releases/jy1261
- Human Rights Watch, Maximum Pressure: US Economic Sanctions Harm Iranians’ Right to Health, 29 Oct 2019, https://www.hrw.org/report/2019/10/29/maximum-pressure/us-economic-sanctions-harm-iranians-right-health
- Weisbrot, Sachs, Economic Sanctions as Collective Punishment: The Case of Venezuela, CEPR, April 2019, https://cepr.net/report-finds-us-sanctions-on-venezuela
- Hausmann, Muci, Don’t Blame Washington for Venezuela’s Oil Woes: A Rebuttal, Americas Quarterly, 1 May 2019, https://www.americasquarterly.org/article/dont-blame-washington-for-venezuelas-oil-woes-a-rebuttal/
- Havana Times (14ymedio), Western Union Suspends Money Transfers to Cuba, 8 Feb 2025, https://havanatimes.org/news/western-union-suspends-money-transfers-to-cuba
- OHCHR, Alena Douhan, end-of-mission statement on Cuba, 21 Nov 2025 (figures “reportedly”), https://www.ecoi.net/en/file/local/2133521/20251121-eom-stm-cuba-sr-negative-impact-unilateral-en.pdf
- Arab News (AFP), citing ONEI: Cuba’s population slide continued in 2025 to 9.4 mn, 22 Jul 2026, https://www.arabnews.pk/node/2651891/world
- Prisoners Defenders, Presos políticos en Cuba, septiembre 2026, 15.10.2026, https://www.prisonersdefenders.org/2026/10/15/presos-politicos-cuba-septiembre-2026/
- Helfen statt Blockieren, Putting the UN vote in context (vote of 28 Oct 2026: 130 yes, 17 no, 25 abstentions)
All online sources accessed on 3 November 2026. Data files for checking: daten/ of this series.
